Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers
Identifieur interne : 005623 ( Main/Exploration ); précédent : 005622; suivant : 005624Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers
Auteurs : Susan J. Ramus [États-Unis] ; Antonis C. Antoniou [Royaume-Uni] ; Karoline B. Kuchenbaecker [Royaume-Uni] ; Penny Soucy [Canada] ; Jonathan Beesley [Australie] ; Xiaoqing Chen [Australie] ; Lesley Mcguffog [Royaume-Uni] ; Olga M. Sinilnikova [France] ; Sue Healey [Australie] ; Daniel Barrowdale [Royaume-Uni] ; Andrew Lee [Royaume-Uni] ; Mads Thomassen [Danemark] ; Anne-Marie Gerdes [Danemark] ; Torben A. Kruse [Danemark] ; Uffe Birk Jensen [Danemark] ; Anne-Bine Skytte [Danemark] ; Maria A. Caligo [Italie] ; Annelie Liljegren [Suède] ; Annika Lindblom [Suède] ; H Kan Olsson [Suède] ; Ulf Kristoffersson [Suède] ; Marie Stenmark-Askmalm [Suède] ; Beatrice Melin [Suède] ; Susan M. Domchek [États-Unis] ; Katherine L. Nathanson [États-Unis] ; Timothy R. Rebbeck [États-Unis] ; Anna Jakubowska [Pologne] ; Jan Lubinski [Pologne] ; Katarzyna Jaworska [Pologne] ; Katarzyna Durda [Pologne] ; El Bieta Złowocka [Pologne] ; Jacek Gronwald [Pologne] ; Tomasz Huzarski [Pologne] ; Tomasz Byrski [Pologne] ; Cezary Cybulski [Pologne] ; Aleksandra Toloczko-Grabarek [Pologne] ; Ana Osorio [Espagne] ; Javier Benitez [Espagne] ; Mercedes Duran [Espagne] ; Maria-Isabel Tejada [Espagne] ; Ute Hamann [Allemagne] ; Matti Rookus [Pays-Bas] ; Flora E. Van Leeuwen [Pays-Bas] ; Cora M. Aalfs [Pays-Bas] ; Hanne E. J. Meijers-Heijboer [Pays-Bas] ; Christi J. Van Asperen [Pays-Bas] ; K. E. P. Van Roozendaal [Pays-Bas] ; Nicoline Hoogerbrugge [Pays-Bas] ; J. Margriet Collée [Pays-Bas] ; Mieke Kriege [Pays-Bas] ; Rob B. Van Der Luijt [Pays-Bas] ; Susan Peock [Royaume-Uni] ; Debra Frost [Royaume-Uni] ; Steve D. Ellis [Royaume-Uni] ; Radka Platte [Royaume-Uni] ; Elena Fineberg [Royaume-Uni] ; D. Gareth Evans [Royaume-Uni] ; Fiona Lalloo [Royaume-Uni] ; Chris Jacobs [Royaume-Uni] ; Ros Eeles [Royaume-Uni] ; Julian Adlard [Royaume-Uni] ; Rosemarie Davidson [Royaume-Uni] ; Diana Eccles [Royaume-Uni] ; Trevor Cole [Royaume-Uni] ; Jackie Cook [Royaume-Uni] ; Joan Paterson [Royaume-Uni] ; Fiona Douglas [Royaume-Uni] ; Carole Brewer [Royaume-Uni] ; Shirley Hodgson [Royaume-Uni] ; Patrick J. Morrison [Royaume-Uni] ; Lisa Walker [Royaume-Uni] ; Mary E. Porteous [Royaume-Uni] ; M. John Kennedy [Irlande (pays)] ; Harsh Pathak [États-Unis] ; Andrew K. Godwin [États-Unis] ; Dominique Stoppa-Lyonnet [France] ; Virginie Caux-Moncoutier [France] ; Antoine De Pauw [France] ; Marion Gauthier-Villars [France] ; Sylvie Mazoyer [France] ; Mélanie Léoné [France] ; Alain Calender [France] ; Christine Lasset [France] ; Valérie Bonadona [France] ; Agnès Hardouin [France] ; Pascaline Berthet [France] ; Yves-Jean Bignon [France] ; Nancy Uhrhammer [France] ; Laurence Faivre [France] ; Catherine Loustalot [France] ; Saundra Buys ; Mary Daly [États-Unis] ; Alex Miron [États-Unis] ; Mary Beth Terry [États-Unis] ; Wendy K. Chung [États-Unis] ; Esther M. John [États-Unis] ; Melissa Southey [Australie] ; David Goldgar [États-Unis] ; Christian F. Singer [Autriche] ; Muy-Kheng Tea [Autriche] ; Georg Pfeiler [Autriche] ; Anneliese Fink-Retter [Autriche] ; Thomas V. O. Hansen [Danemark] ; Bent Ejlertsen [Danemark] ; Oskar Th. Johannsson [Islande] ; Kenneth Offit [États-Unis] ; Tomas Kirchhoff [États-Unis] ; Mia M. Gaudet [Géorgie (pays)] ; Joseph Vijai [États-Unis] ; Mark Robson [États-Unis] ; Marion Piedmonte [États-Unis] ; Kelly-Anne Phillips [Australie] ; Linda Van Le [États-Unis] ; James S. Hoffman ; Amanda Ewart Toland [États-Unis] ; Marco Montagna [Italie] ; Silvia Tognazzo [Italie] ; Evgeny Imyanitov [Russie] ; Claudine Isaacs [États-Unis] ; Ramunas Janavicius [Lituanie] ; Conxi Lazaro [Espagne] ; Ignacio Blanco [Espagne] ; Eva Tornero [Espagne] ; Matilde Navarro [Espagne] ; Kirsten B. Moysich [États-Unis] ; Beth Y. Karlan [États-Unis] ; Jenny Gross [États-Unis] ; Edith Olah [Hongrie] ; Tibor Vaszko [Hongrie] ; Soo-Hwang Teo [Malaisie] ; Patricia A. Ganz [États-Unis] ; Mary S. Beattie [États-Unis] ; Cecelia M. Dorfling [Afrique du Sud] ; Elizabeth J. Van Rensburg [Afrique du Sud] ; Orland Diez [Espagne] ; Ava Kwong [Hong Kong] ; Rita K. Schmutzler [Allemagne] ; Barbara Wappenschmidt [Allemagne] ; Christoph Engel [Allemagne] ; Alfons Meindl [Allemagne] ; Nina Ditsch [Allemagne] ; Norbert Arnold [Allemagne] ; Simone Heidemann [Allemagne] ; Dieter Niederacher [Allemagne] ; Sabine Preisler-Adams [Allemagne] ; Dorotehea Gadzicki [Allemagne] ; Raymonda Varon-Mateeva [Allemagne] ; Helmut Deissler [Allemagne] ; Andrea Gehrig [Allemagne] ; Christian Sutter [Allemagne] ; Karin Kast [Allemagne] ; Britta Fiebig [Allemagne] ; Dieter Sch Fer [Allemagne] ; Trinidad Caldes [Espagne] ; Miguel De La Hoya [Espagne] ; Heli Nevanlinna [Finlande] ; Kristiina Aittom Ki [Finlande] ; Marie Plante [Canada] ; Amanda B. Spurdle [Australie] ; Susan L. Neuhausen [États-Unis] ; Yuan Chun Ding [États-Unis] ; Xianshu Wang [États-Unis] ; Noralane Lindor [États-Unis] ; Zachary Fredericksen [États-Unis] ; V. Shane Pankratz [États-Unis] ; Paolo Peterlongo [Italie] ; Siranoush Manoukian [Italie] ; Bernard Peissel [Italie] ; Daniela Zaffaroni [Italie] ; Bernardo Bonanni [Italie] ; Loris Bernard [Italie] ; Riccardo Dolcetti [Italie] ; Laura Papi [Italie] ; Laura Ottini [Italie] ; Paolo Radice [Italie] ; Mark H. Greene [États-Unis] ; Phuong L. Mai [États-Unis] ; Irene L. Andrulis [Canada] ; Gord Glendon [Canada] ; Hilmi Ozcelik [Canada] ; Paul D. P. Pharoah [Royaume-Uni] ; Simon A. Gayther [États-Unis] ; Jacques Simard [Canada] ; Douglas F. Easton [Royaume-Uni] ; Fergus J. Couch [États-Unis] ; Georgia Chenevix-Trench [Australie]Source :
- Human Mutation [ 1059-7794 ] ; 2012-04.
Descripteurs français
- Wicri :
- geographic : Pays-Bas.
- topic : Cancer, Transporteur, Consortium, épidémiologie, Génétique, Gynécologie, Santé publique.
English descriptors
- KwdEn :
- Allele, Allele brca1, Allele brca2, Antoniou, Association study, Brca1, Brca1 brca2 mutation carriers, Brca1 carriers, Brca1 mutation carriers, Brca2, Brca2 carriers, Brca2 mutation carriers, Brca2 mutations, Breast, Breast cancer, Breast cancer family registry, Breast cancer linkage consortium, Breast cancer research foundation, Breast cancer risk, Cancer, Cancer care ontario, Cancer center, Cancer genetics network, Cancer institute, Cancer prevention, Cancer research, Cancer risk, Carrier, Centre, Centre hospitalier universitaire, Chase cancer center, Cimba, Clinical genetics, Common variants, Consortium, Easton, Epidemiology, Familial breast cancer, Fondazione, Fondazione irccs istituto nazionale tumori, Foundation trust, General population, Genet, Genet antoniou, Genetics, Genetics service, Genotype, Genotyping, Gilda radner, Grant number, Gwas, Gynaecology, Gynecologic oncology group, Healey, Helsinki, Helsinki university, Hereditary breast, Hong kong, Human genetics, Human mutation, Istituto, Istituto europeo, Karolinska university hospital, Laboratory medicine, Locus, Lund university hospital, Many others, Mayo clinic, Medical genetics, Milan, Ministero della salute, Minor allele, Molecular genetics, Molecular medicine, Mutation, Mutation carriers, National cancer institute, National institutes, Netherlands, Netherlands cancer institute, Obstetrics, Ohio state university, Oncology, Ontario, Ontario cancer genetics network, Ovarian, Ovarian cancer, Ovarian cancer cases, Ovarian cancer gwas, Ovarian cancer risk, Primary analysis, Primary care, Principal research fellow, Public health, Ramus, Royal marsden, Senior cancer research fellow, Sinilnikova, Snp, Susceptibility, Technical support, Tumori, University hospital.
- Teeft :
- Allele, Allele brca1, Allele brca2, Antoniou, Association study, Brca1, Brca1 brca2 mutation carriers, Brca1 carriers, Brca1 mutation carriers, Brca2, Brca2 carriers, Brca2 mutation carriers, Brca2 mutations, Breast, Breast cancer, Breast cancer family registry, Breast cancer linkage consortium, Breast cancer research foundation, Breast cancer risk, Cancer, Cancer care ontario, Cancer center, Cancer genetics network, Cancer institute, Cancer prevention, Cancer research, Cancer risk, Carrier, Centre, Centre hospitalier universitaire, Chase cancer center, Cimba, Clinical genetics, Common variants, Consortium, Easton, Epidemiology, Familial breast cancer, Fondazione, Fondazione irccs istituto nazionale tumori, Foundation trust, General population, Genet, Genet antoniou, Genetics, Genetics service, Genotype, Genotyping, Gilda radner, Grant number, Gwas, Gynaecology, Gynecologic oncology group, Healey, Helsinki, Helsinki university, Hereditary breast, Hong kong, Human genetics, Human mutation, Istituto, Istituto europeo, Karolinska university hospital, Laboratory medicine, Locus, Lund university hospital, Many others, Mayo clinic, Medical genetics, Milan, Ministero della salute, Minor allele, Molecular genetics, Molecular medicine, Mutation, Mutation carriers, National cancer institute, National institutes, Netherlands, Netherlands cancer institute, Obstetrics, Ohio state university, Oncology, Ontario, Ontario cancer genetics network, Ovarian, Ovarian cancer, Ovarian cancer cases, Ovarian cancer gwas, Ovarian cancer risk, Primary analysis, Primary care, Principal research fellow, Public health, Ramus, Royal marsden, Senior cancer research fellow, Sinilnikova, Snp, Susceptibility, Technical support, Tumori, University hospital.
Abstract
Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome‐wide association study (GWAS) identified six alleles associated with risk of ovarian cancer for women in the general population. We evaluated four of these loci as potential modifiers of ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Four single‐nucleotide polymorphisms (SNPs), rs10088218 (at 8q24), rs2665390 (at 3q25), rs717852 (at 2q31), and rs9303542 (at 17q21), were genotyped in 12,599 BRCA1 and 7,132 BRCA2 carriers, including 2,678 ovarian cancer cases. Associations were evaluated within a retrospective cohort approach. All four loci were associated with ovarian cancer risk in BRCA2 carriers; rs10088218 per‐allele hazard ratio (HR) = 0.81 (95% CI: 0.67–0.98) P‐trend = 0.033, rs2665390 HR = 1.48 (95% CI: 1.21–1.83) P‐trend = 1.8 × 10−4, rs717852 HR = 1.25 (95% CI: 1.10–1.42) P‐trend = 6.6 × 10−4, rs9303542 HR = 1.16 (95% CI: 1.02–1.33) P‐trend = 0.026. Two loci were associated with ovarian cancer risk in BRCA1 carriers; rs10088218 per‐allele HR = 0.89 (95% CI: 0.81–0.99) P‐trend = 0.029, rs2665390 HR = 1.25 (95% CI: 1.10–1.42) P‐trend = 6.1 × 10−4. The HR estimates for the remaining loci were consistent with odds ratio estimates for the general population. The identification of multiple loci modifying ovarian cancer risk may be useful for counseling women with BRCA1 and BRCA2 mutations regarding their risk of ovarian cancer. Hum Mutat 33:690–702, 2012. © 2012 Wiley Periodicals, Inc.
Url:
- https://api.istex.fr/document/65C47E97FAD911B8DA21E60FA7242862E43652F1/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458423
DOI: 10.1002/humu.22025
Affiliations:
- Afrique du Sud, Allemagne, Australie, Autriche, Canada, Danemark, Espagne, Finlande, France, Géorgie (pays), Hong Kong, Hongrie, Irlande (pays), Islande, Italie, Lituanie, Malaisie, Pays-Bas, Pologne, Royaume-Uni, Russie, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Auvergne-Rhône-Alpes, Bade-Wurtemberg, Basse-Normandie, Basse-Saxe, Bavière, Bourgogne, Bourgogne-Franche-Comté, Californie, Caroline du Nord, Catalogne, Communauté de Madrid, District de Columbia, District de Darmstadt, District de Dresde, District de Düsseldorf, District de Haute-Bavière, District de Karlsruhe, District de Leipzig, District de Münster, District de Tübingen, Grand Londres, Grand Manchester, Gueldre, Hesse (Land), Hollande-Méridionale, Hollande-Septentrionale, Hongrie centrale, Hovedstaden, Kansas, Latium, Lombardie, Maryland, Massachusetts, Midlands de l'Ouest, Minnesota, Ohio, Ontario, Oxfordshire, Pennsylvanie, Rhénanie-du-Nord-Westphalie, Rhône-Alpes, Région Normandie, Saxe (Land), Schleswig-Holstein, Svealand, Toscane, Utah, Victoria (État), Vienne (Autriche), Écosse, État de New York, Île-de-France
- Amsterdam, Barcelone, Birmingham, Budapest, Caen, Cambridge, Copenhague, Dijon, Dresde, Düsseldorf, Francfort-sur-le-Main, Hanovre, Heidelberg, Kiel, Leipzig, Leyde, Londres, Lyon, Madrid, Manchester, Melbourne, Milan, Munich, Münster, Nimègue, Oxford, Paris, Pise, Rome, Rotterdam, Stockholm, Toronto, Ulm, Vienne (Autriche), Washington (district de Columbia), Édimbourg
- Université Paris-Descartes, Université de Bourgogne, Université de Cambridge, Université de Londres, Université de Melbourne, Université de Toronto
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Le document en format XML
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Margriet" last="Collée">J. Margriet Collée</name></author><author><name sortKey="Kriege, Mieke" sort="Kriege, Mieke" uniqKey="Kriege M" first="Mieke" last="Kriege">Mieke Kriege</name></author><author><name sortKey="Van Der Luijt, Rob B" sort="Van Der Luijt, Rob B" uniqKey="Van Der Luijt R" first="Rob B." last="Van Der Luijt">Rob B. Van Der Luijt</name></author><author><name sortKey="Peock, Susan" sort="Peock, Susan" uniqKey="Peock S" first="Susan" last="Peock">Susan Peock</name></author><author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name></author><author><name sortKey="Ellis, Steve D" sort="Ellis, Steve D" uniqKey="Ellis S" first="Steve D." last="Ellis">Steve D. Ellis</name></author><author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name></author><author><name sortKey="Fineberg, Elena" sort="Fineberg, Elena" uniqKey="Fineberg E" first="Elena" last="Fineberg">Elena Fineberg</name></author><author><name sortKey="Evans, D Gareth" sort="Evans, D Gareth" uniqKey="Evans D" first="D. Gareth" last="Evans">D. Gareth Evans</name></author><author><name sortKey="Lalloo, Fiona" sort="Lalloo, Fiona" uniqKey="Lalloo F" first="Fiona" last="Lalloo">Fiona Lalloo</name></author><author><name sortKey="Jacobs, Chris" sort="Jacobs, Chris" uniqKey="Jacobs C" first="Chris" last="Jacobs">Chris Jacobs</name></author><author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name></author><author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name></author><author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name></author><author><name sortKey="Cole, Trevor" sort="Cole, Trevor" uniqKey="Cole T" first="Trevor" last="Cole">Trevor Cole</name></author><author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name></author><author><name sortKey="Paterson, Joan" sort="Paterson, Joan" uniqKey="Paterson J" first="Joan" last="Paterson">Joan Paterson</name></author><author><name sortKey="Douglas, Fiona" sort="Douglas, Fiona" uniqKey="Douglas F" first="Fiona" last="Douglas">Fiona Douglas</name></author><author><name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name></author><author><name sortKey="Hodgson, Shirley" sort="Hodgson, Shirley" uniqKey="Hodgson S" first="Shirley" last="Hodgson">Shirley Hodgson</name></author><author><name sortKey="Morrison, Patrick J" sort="Morrison, Patrick J" uniqKey="Morrison P" first="Patrick J." last="Morrison">Patrick J. Morrison</name></author><author><name sortKey="Walker, Lisa" sort="Walker, Lisa" uniqKey="Walker L" first="Lisa" last="Walker">Lisa Walker</name></author><author><name sortKey="Porteous, Mary E" sort="Porteous, Mary E" uniqKey="Porteous M" first="Mary E." last="Porteous">Mary E. Porteous</name></author><author><name sortKey="Kennedy, M John" sort="Kennedy, M John" uniqKey="Kennedy M" first="M. John" last="Kennedy">M. John Kennedy</name></author><author><name sortKey="Pathak, Harsh" sort="Pathak, Harsh" uniqKey="Pathak H" first="Harsh" last="Pathak">Harsh Pathak</name></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K." last="Godwin">Andrew K. Godwin</name></author><author><name sortKey="Stoppa Yonnet, Dominique" sort="Stoppa Yonnet, Dominique" uniqKey="Stoppa Yonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name></author><author><name sortKey="Caux Oncoutier, Virginie" sort="Caux Oncoutier, Virginie" uniqKey="Caux Oncoutier V" first="Virginie" last="Caux-Moncoutier">Virginie Caux-Moncoutier</name></author><author><name sortKey="De Pauw, Antoine" sort="De Pauw, Antoine" uniqKey="De Pauw A" first="Antoine" last="De Pauw">Antoine De Pauw</name></author><author><name sortKey="Gauthier Illars, Marion" sort="Gauthier Illars, Marion" uniqKey="Gauthier Illars M" first="Marion" last="Gauthier-Villars">Marion Gauthier-Villars</name></author><author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name></author><author><name sortKey="Leone, Melanie" sort="Leone, Melanie" uniqKey="Leone M" first="Mélanie" last="Léoné">Mélanie Léoné</name></author><author><name sortKey="Calender, Alain" sort="Calender, Alain" uniqKey="Calender A" first="Alain" last="Calender">Alain Calender</name></author><author><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name></author><author><name sortKey="Bonadona, Valerie" sort="Bonadona, Valerie" uniqKey="Bonadona V" first="Valérie" last="Bonadona">Valérie Bonadona</name></author><author><name sortKey="Hardouin, Agnes" sort="Hardouin, Agnes" uniqKey="Hardouin A" first="Agnès" last="Hardouin">Agnès Hardouin</name></author><author><name sortKey="Berthet, Pascaline" sort="Berthet, Pascaline" uniqKey="Berthet P" first="Pascaline" last="Berthet">Pascaline Berthet</name></author><author><name sortKey="Bignon, Yves Ean" sort="Bignon, Yves Ean" uniqKey="Bignon Y" first="Yves-Jean" last="Bignon">Yves-Jean Bignon</name></author><author><name sortKey="Uhrhammer, Nancy" sort="Uhrhammer, Nancy" uniqKey="Uhrhammer N" first="Nancy" last="Uhrhammer">Nancy Uhrhammer</name></author><author><name sortKey="Faivre, Laurence" sort="Faivre, Laurence" uniqKey="Faivre L" first="Laurence" last="Faivre">Laurence Faivre</name></author><author><name sortKey="Loustalot, Catherine" sort="Loustalot, Catherine" uniqKey="Loustalot C" first="Catherine" last="Loustalot">Catherine Loustalot</name></author><author><name sortKey="Buys, Saundra" sort="Buys, Saundra" uniqKey="Buys S" first="Saundra" last="Buys">Saundra Buys</name></author><author><name sortKey="Daly, Mary" sort="Daly, Mary" uniqKey="Daly M" first="Mary" last="Daly">Mary Daly</name></author><author><name sortKey="Miron, Alex" sort="Miron, Alex" uniqKey="Miron A" first="Alex" last="Miron">Alex Miron</name></author><author><name sortKey="Beth Terry, Mary" sort="Beth Terry, Mary" uniqKey="Beth Terry M" first="Mary" last="Beth Terry">Mary Beth Terry</name></author><author><name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K." last="Chung">Wendy K. Chung</name></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M" last="John">Esther M. John</name></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name></author><author><name sortKey="Goldgar, David" sort="Goldgar, David" uniqKey="Goldgar D" first="David" last="Goldgar">David Goldgar</name></author><author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F." last="Singer">Christian F. Singer</name></author><author><name sortKey="Tea, Muy Heng" sort="Tea, Muy Heng" uniqKey="Tea M" first="Muy-Kheng" last="Tea">Muy-Kheng Tea</name></author><author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name></author><author><name sortKey="Fink Etter, Anneliese" sort="Fink Etter, Anneliese" uniqKey="Fink Etter A" first="Anneliese" last="Fink-Retter">Anneliese Fink-Retter</name></author><author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name></author><author><name sortKey="Johannsson, Oskar Th" sort="Johannsson, Oskar Th" uniqKey="Johannsson O" first="Oskar Th." last="Johannsson">Oskar Th. Johannsson</name></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name></author><author><name sortKey="Kirchhoff, Tomas" sort="Kirchhoff, Tomas" uniqKey="Kirchhoff T" first="Tomas" last="Kirchhoff">Tomas Kirchhoff</name></author><author><name sortKey="Gaudet, Mia M" sort="Gaudet, Mia M" uniqKey="Gaudet M" first="Mia M." last="Gaudet">Mia M. Gaudet</name></author><author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name></author><author><name sortKey="Robson, Mark" sort="Robson, Mark" uniqKey="Robson M" first="Mark" last="Robson">Mark Robson</name></author><author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name></author><author><name sortKey="Phillips, Kelly Nne" sort="Phillips, Kelly Nne" uniqKey="Phillips K" first="Kelly-Anne" last="Phillips">Kelly-Anne Phillips</name></author><author><name sortKey="Van Le, Linda" sort="Van Le, Linda" uniqKey="Van Le L" first="Linda" last="Van Le">Linda Van Le</name></author><author><name sortKey="Hoffman, James S" sort="Hoffman, James S" uniqKey="Hoffman J" first="James S" last="Hoffman">James S. Hoffman</name></author><author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name></author><author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name></author><author><name sortKey="Tognazzo, Silvia" sort="Tognazzo, Silvia" uniqKey="Tognazzo S" first="Silvia" last="Tognazzo">Silvia Tognazzo</name></author><author><name sortKey="Imyanitov, Evgeny" sort="Imyanitov, Evgeny" uniqKey="Imyanitov E" first="Evgeny" last="Imyanitov">Evgeny Imyanitov</name></author><author><name sortKey="Isaacs, Claudine" sort="Isaacs, Claudine" uniqKey="Isaacs C" first="Claudine" last="Isaacs">Claudine Isaacs</name></author><author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name></author><author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name></author><author><name sortKey="Blanco, Ignacio" sort="Blanco, Ignacio" uniqKey="Blanco I" first="Ignacio" last="Blanco">Ignacio Blanco</name></author><author><name sortKey="Tornero, Eva" sort="Tornero, Eva" uniqKey="Tornero E" first="Eva" last="Tornero">Eva Tornero</name></author><author><name sortKey="Navarro, Matilde" sort="Navarro, Matilde" uniqKey="Navarro M" first="Matilde" last="Navarro">Matilde Navarro</name></author><author><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B." last="Moysich">Kirsten B. Moysich</name></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name></author><author><name sortKey="Gross, Jenny" sort="Gross, Jenny" uniqKey="Gross J" first="Jenny" last="Gross">Jenny Gross</name></author><author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name></author><author><name sortKey="Vaszko, Tibor" sort="Vaszko, Tibor" uniqKey="Vaszko T" first="Tibor" last="Vaszko">Tibor Vaszko</name></author><author><name sortKey="Teo, Soo Wang" sort="Teo, Soo Wang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name></author><author><name sortKey="Ganz, Patricia A" sort="Ganz, Patricia A" uniqKey="Ganz P" first="Patricia A." last="Ganz">Patricia A. Ganz</name></author><author><name sortKey="Beattie, Mary S" sort="Beattie, Mary S" uniqKey="Beattie M" first="Mary S." last="Beattie">Mary S. Beattie</name></author><author><name sortKey="Dorfling, Cecelia M" sort="Dorfling, Cecelia M" uniqKey="Dorfling C" first="Cecelia M" last="Dorfling">Cecelia M. Dorfling</name></author><author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J." last="Van Rensburg">Elizabeth J. Van Rensburg</name></author><author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name></author><author><name sortKey="Kwong, Ava" sort="Kwong, Ava" uniqKey="Kwong A" first="Ava" last="Kwong">Ava Kwong</name></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name></author><author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name></author><author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name></author><author><name sortKey="Ditsch, Nina" sort="Ditsch, Nina" uniqKey="Ditsch N" first="Nina" last="Ditsch">Nina Ditsch</name></author><author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name></author><author><name sortKey="Heidemann, Simone" sort="Heidemann, Simone" uniqKey="Heidemann S" first="Simone" last="Heidemann">Simone Heidemann</name></author><author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name></author><author><name sortKey="Preisler Dams, Sabine" sort="Preisler Dams, Sabine" uniqKey="Preisler Dams S" first="Sabine" last="Preisler-Adams">Sabine Preisler-Adams</name></author><author><name sortKey="Gadzicki, Dorotehea" sort="Gadzicki, Dorotehea" uniqKey="Gadzicki D" first="Dorotehea" last="Gadzicki">Dorotehea Gadzicki</name></author><author><name sortKey="Varon Ateeva, Raymonda" sort="Varon Ateeva, Raymonda" uniqKey="Varon Ateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name></author><author><name sortKey="Deissler, Helmut" sort="Deissler, Helmut" uniqKey="Deissler H" first="Helmut" last="Deissler">Helmut Deissler</name></author><author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name></author><author><name sortKey="Sutter, Christian" sort="Sutter, Christian" uniqKey="Sutter C" first="Christian" last="Sutter">Christian Sutter</name></author><author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name></author><author><name sortKey="Fiebig, Britta" sort="Fiebig, Britta" uniqKey="Fiebig B" first="Britta" last="Fiebig">Britta Fiebig</name></author><author><name sortKey="Sch Fer, Dieter" sort="Sch Fer, Dieter" uniqKey="Sch Fer D" first="Dieter" last="Sch Fer">Dieter Sch Fer</name></author><author><name sortKey="Caldes, Trinidad" sort="Caldes, Trinidad" uniqKey="Caldes T" first="Trinidad" last="Caldes">Trinidad Caldes</name></author><author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name></author><author><name sortKey="Plante, Marie" sort="Plante, Marie" uniqKey="Plante M" first="Marie" last="Plante">Marie Plante</name></author><author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name></author><author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L." last="Neuhausen">Susan L. Neuhausen</name></author><author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name></author><author><name sortKey="Lindor, Noralane" sort="Lindor, Noralane" uniqKey="Lindor N" first="Noralane" last="Lindor">Noralane Lindor</name></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name></author><author><name sortKey="Pankratz, V Shane" sort="Pankratz, V Shane" uniqKey="Pankratz V" first="V. Shane" last="Pankratz">V. Shane Pankratz</name></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name></author><author><name sortKey="Zaffaroni, Daniela" sort="Zaffaroni, Daniela" uniqKey="Zaffaroni D" first="Daniela" last="Zaffaroni">Daniela Zaffaroni</name></author><author><name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name></author><author><name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name></author><author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name></author><author><name sortKey="Ottini, Laura" sort="Ottini, Laura" uniqKey="Ottini L" first="Laura" last="Ottini">Laura Ottini</name></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H." last="Greene">Mark H. Greene</name></author><author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L." last="Mai">Phuong L. Mai</name></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name></author><author><name sortKey="Ozcelik, Hilmi" sort="Ozcelik, Hilmi" uniqKey="Ozcelik H" first="Hilmi" last="Ozcelik">Hilmi Ozcelik</name></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name></author><author><name sortKey="Gayther, Simon A" sort="Gayther, Simon A" uniqKey="Gayther S" first="Simon A." last="Gayther">Simon A. Gayther</name></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name></author><author><name sortKey="Chenevix Rench, Georgia" sort="Chenevix Rench, Georgia" uniqKey="Chenevix Rench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:65C47E97FAD911B8DA21E60FA7242862E43652F1</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/humu.22025</idno><idno type="url">https://api.istex.fr/document/65C47E97FAD911B8DA21E60FA7242862E43652F1/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001312</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001312</idno><idno type="wicri:Area/Istex/Curation">001312</idno><idno type="wicri:Area/Istex/Checkpoint">000548</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000548</idno><idno type="wicri:doubleKey">1059-7794:2012:Ramus S:ovarian:cancer:susceptibility</idno><idno type="wicri:source">PMC</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458423</idno><idno type="RBID">PMC:3458423</idno><idno type="wicri:Area/Pmc/Corpus">002111</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002111</idno><idno type="wicri:Area/Pmc/Curation">001F65</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001F65</idno><idno type="wicri:Area/Pmc/Checkpoint">001E20</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001E20</idno><idno type="wicri:Area/Ncbi/Merge">000C83</idno><idno type="wicri:Area/Ncbi/Curation">000C83</idno><idno type="wicri:Area/Ncbi/Checkpoint">000C83</idno><idno type="wicri:doubleKey">1059-7794:2012:Ramus S:ovarian:cancer:susceptibility</idno><idno type="wicri:Area/Main/Merge">005890</idno><idno type="wicri:Area/Main/Curation">005623</idno><idno type="wicri:Area/Main/Exploration">005623</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Ovarian cancer susceptibility alleles and risk of ovarian cancer in <hi rend="italic">BRCA1</hi> and <hi rend="italic">BRCA2</hi> mutation carriers<ref type="note" target="#fn1"></ref></title><author><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J." last="Ramus">Susan J. Ramus</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</wicri:cityArea></affiliation></author><author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Royaume-Uni</country></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Correspondence address: Cancer Research UK Senior Cancer Research Fellow, Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Kuchenbaecker, Karoline B" sort="Kuchenbaecker, Karoline B" uniqKey="Kuchenbaecker K" first="Karoline B." last="Kuchenbaecker">Karoline B. Kuchenbaecker</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City</wicri:regionArea><wicri:noRegion>Quebec City</wicri:noRegion></affiliation></author><author><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Genetics and Population Health Division, Queensland Institute of Medical Research, Herston</wicri:regionArea><wicri:noRegion>Herston</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Genetics and Population Health Division, Queensland Institute of Medical Research, Herston</wicri:regionArea><wicri:noRegion>Herston</wicri:noRegion></affiliation></author><author><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Sinilnikova, Olga M" sort="Sinilnikova, Olga M" uniqKey="Sinilnikova O" first="Olga M." last="Sinilnikova">Olga M. Sinilnikova</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Centre Hospitalier Universitaire de Lyon / Centre Léon Bérard, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Genetics and Population Health Division, Queensland Institute of Medical Research, Herston</wicri:regionArea><wicri:noRegion>Herston</wicri:noRegion></affiliation></author><author><name sortKey="Barrowdale, Daniel" sort="Barrowdale, Daniel" uniqKey="Barrowdale D" first="Daniel" last="Barrowdale">Daniel Barrowdale</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Lee, Andrew" sort="Lee, Andrew" uniqKey="Lee A" first="Andrew" last="Lee">Andrew Lee</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Gerdes, Anne Arie" sort="Gerdes, Anne Arie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clincial Genetics, Rigshospital and Copenhagen University, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Kruse, Torben A" sort="Kruse, Torben A" uniqKey="Kruse T" first="Torben A." last="Kruse">Torben A. Kruse</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Odense University Hospital, Odense</wicri:regionArea><wicri:noRegion>Odense</wicri:noRegion></affiliation></author><author><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Skejby Hospital, Aarhus</wicri:regionArea><wicri:noRegion>Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Skytte, Anne Ine" sort="Skytte, Anne Ine" uniqKey="Skytte A" first="Anne-Bine" last="Skytte">Anne-Bine Skytte</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Genetics, Vejle Hospital, Vejle</wicri:regionArea><wicri:noRegion>Vejle</wicri:noRegion></affiliation></author><author><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A." last="Caligo">Maria A. Caligo</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region></placeName></affiliation></author><author><name sortKey="Liljegren, Annelie" sort="Liljegren, Annelie" uniqKey="Liljegren A" first="Annelie" last="Liljegren">Annelie Liljegren</name><affiliation wicri:level="3"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology, Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><affiliation wicri:level="3"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Genetics, Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Olsson, H Kan" sort="Olsson, H Kan" uniqKey="Olsson H" first="H Kan" last="Olsson">H Kan Olsson</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology, Lund University Hospital, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Kristoffersson, Ulf" sort="Kristoffersson, Ulf" uniqKey="Kristoffersson U" first="Ulf" last="Kristoffersson">Ulf Kristoffersson</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Genetics, Lund University Hospital, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Stenmark Skmalm, Marie" sort="Stenmark Skmalm, Marie" uniqKey="Stenmark Skmalm M" first="Marie" last="Stenmark-Askmalm">Marie Stenmark-Askmalm</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, Linkoping</wicri:regionArea><wicri:noRegion>Linkoping</wicri:noRegion></affiliation></author><author><name sortKey="Melin, Beatrice" sort="Melin, Beatrice" uniqKey="Melin B" first="Beatrice" last="Melin">Beatrice Melin</name><affiliation wicri:level="1"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Radiation Sciences, Oncology, Umeå University, Umea</wicri:regionArea><wicri:noRegion>Umea</wicri:noRegion></affiliation></author><author><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M." last="Domchek">Susan M. Domchek</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Abramson Cancer Center, and Perelman School of Medicine, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L." last="Nathanson">Katherine L. Nathanson</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Abramson Cancer Center, and Perelman School of Medicine, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Rebbeck, Timothy R" sort="Rebbeck, Timothy R" uniqKey="Rebbeck T" first="Timothy R." last="Rebbeck">Timothy R. Rebbeck</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Abramson Cancer Center, and Perelman School of Medicine, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Zlowocka, El Bieta" sort="Zlowocka, El Bieta" uniqKey="Zlowocka E" first="El Bieta" last="Złowocka">El Bieta Złowocka</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Huzarski, Tomasz" sort="Huzarski, Tomasz" uniqKey="Huzarski T" first="Tomasz" last="Huzarski">Tomasz Huzarski</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Byrski, Tomasz" sort="Byrski, Tomasz" uniqKey="Byrski T" first="Tomasz" last="Byrski">Tomasz Byrski</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Toloczko Rabarek, Aleksandra" sort="Toloczko Rabarek, Aleksandra" uniqKey="Toloczko Rabarek A" first="Aleksandra" last="Toloczko-Grabarek">Aleksandra Toloczko-Grabarek</name><affiliation wicri:level="1"><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Osorio, Ana" sort="Osorio, Ana" uniqKey="Osorio A" first="Ana" last="Osorio">Ana Osorio</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain, and Biomedical Network on Rare Diseases (CIBERER), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain, and Biomedical Network on Rare Diseases (CIBERER), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Duran, Mercedes" sort="Duran, Mercedes" uniqKey="Duran M" first="Mercedes" last="Duran">Mercedes Duran</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Institute of Biology and Molecular Genetics, University of Valladolid, Valladolid</wicri:regionArea><wicri:noRegion>Valladolid</wicri:noRegion></affiliation></author><author><name sortKey="Tejada, Maria Sabel" sort="Tejada, Maria Sabel" uniqKey="Tejada M" first="Maria-Isabel" last="Tejada">Maria-Isabel Tejada</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Molecular Genetics Laboratory, Cruces Hospital Barakaldo, Bizkaia</wicri:regionArea><wicri:noRegion>Bizkaia</wicri:noRegion></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Rookus, Matti" sort="Rookus, Matti" uniqKey="Rookus M" first="Matti" last="Rookus">Matti Rookus</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Netherlands Cancer Institute, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Van Leeuwen, Flora E" sort="Van Leeuwen, Flora E" uniqKey="Van Leeuwen F" first="Flora E." last="Van Leeuwen">Flora E. Van Leeuwen</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Division of Psychosocial Research & Epidemiology, Netherlands Cancer Institute, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Aalfs, Cora M" sort="Aalfs, Cora M" uniqKey="Aalfs C" first="Cora M." last="Aalfs">Cora M. Aalfs</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Clinical Genetics, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Meijers Eijboer, Hanne E J" sort="Meijers Eijboer, Hanne E J" uniqKey="Meijers Eijboer H" first="Hanne E. J." last="Meijers-Heijboer">Hanne E. J. Meijers-Heijboer</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Clinical Genetics, VU Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Clinical Genetics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Roozendaal, K E P" sort="Van Roozendaal, K E P" uniqKey="Van Roozendaal K" first="K. E. P." last="Van Roozendaal">K. E. P. Van Roozendaal</name><affiliation wicri:level="1"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Clinical Genomics, MUMC, Maastricht</wicri:regionArea><wicri:noRegion>Maastricht</wicri:noRegion></affiliation></author><author><name sortKey="Hoogerbrugge, Nicoline" sort="Hoogerbrugge, Nicoline" uniqKey="Hoogerbrugge N" first="Nicoline" last="Hoogerbrugge">Nicoline Hoogerbrugge</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Hereditary Cancer Clinic, Radboud University Nijmegen Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Collee, J Margriet" sort="Collee, J Margriet" uniqKey="Collee J" first="J. Margriet" last="Collée">J. Margriet Collée</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Kriege, Mieke" sort="Kriege, Mieke" uniqKey="Kriege M" first="Mieke" last="Kriege">Mieke Kriege</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Der Luijt, Rob B" sort="Van Der Luijt, Rob B" uniqKey="Van Der Luijt R" first="Rob B." last="Van Der Luijt">Rob B. Van Der Luijt</name><affiliation wicri:level="1"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht</wicri:regionArea><wicri:noRegion>University Medical Center Utrecht</wicri:noRegion></affiliation></author><author><name sortKey="Peock, Susan" sort="Peock, Susan" uniqKey="Peock S" first="Susan" last="Peock">Susan Peock</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Ellis, Steve D" sort="Ellis, Steve D" uniqKey="Ellis S" first="Steve D." last="Ellis">Steve D. Ellis</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Fineberg, Elena" sort="Fineberg, Elena" uniqKey="Fineberg E" first="Elena" last="Fineberg">Elena Fineberg</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Evans, D Gareth" sort="Evans, D Gareth" uniqKey="Evans D" first="D. Gareth" last="Evans">D. Gareth Evans</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Lalloo, Fiona" sort="Lalloo, Fiona" uniqKey="Lalloo F" first="Fiona" last="Lalloo">Fiona Lalloo</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Jacobs, Chris" sort="Jacobs, Chris" uniqKey="Jacobs C" first="Chris" last="Jacobs">Chris Jacobs</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Yorkshire Regional Genetics Service, Leeds</wicri:regionArea><wicri:noRegion>Leeds</wicri:noRegion></affiliation></author><author><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ferguson‐Smith Centre for Clinical Genetics, Yorkhill Hospitals, Glasgow</wicri:regionArea><wicri:noRegion>Glasgow</wicri:noRegion></affiliation></author><author><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Southampton Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Cole, Trevor" sort="Cole, Trevor" uniqKey="Cole T" first="Trevor" last="Cole">Trevor Cole</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield</wicri:regionArea><wicri:noRegion>Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Paterson, Joan" sort="Paterson, Joan" uniqKey="Paterson J" first="Joan" last="Paterson">Joan Paterson</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Genetics, East Anglian Regional Genetics Service, Addenbrookes Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Douglas, Fiona" sort="Douglas, Fiona" uniqKey="Douglas F" first="Fiona" last="Douglas">Fiona Douglas</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Genetic Medicine, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle Upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Hodgson, Shirley" sort="Hodgson, Shirley" uniqKey="Hodgson S" first="Shirley" last="Hodgson">Shirley Hodgson</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Genetics Unit, St George's, University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Morrison, Patrick J" sort="Morrison, Patrick J" uniqKey="Morrison P" first="Patrick J." last="Morrison">Patrick J. Morrison</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Northern Ireland Regional Genetics Centre, Belfast Health and Social Care Trust, and Department of Medical Genetics, Queens University Belfast, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Walker, Lisa" sort="Walker, Lisa" uniqKey="Walker L" first="Lisa" last="Walker">Lisa Walker</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxford Regional Genetics Service, Churchill Hospital, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Porteous, Mary E" sort="Porteous, Mary E" uniqKey="Porteous M" first="Mary E." last="Porteous">Mary E. Porteous</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Kennedy, M John" sort="Kennedy, M John" uniqKey="Kennedy M" first="M. John" last="Kennedy">M. John Kennedy</name><affiliation wicri:level="1"><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin and St James's Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Pathak, Harsh" sort="Pathak, Harsh" uniqKey="Pathak H" first="Harsh" last="Pathak">Harsh Pathak</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Kansas</region></placeName><wicri:cityArea>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City</wicri:cityArea></affiliation></author><author><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K." last="Godwin">Andrew K. Godwin</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Kansas</region></placeName><wicri:cityArea>Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City</wicri:cityArea></affiliation></author><author><name sortKey="Stoppa Yonnet, Dominique" sort="Stoppa Yonnet, Dominique" uniqKey="Stoppa Yonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Génétique Oncologique, Institut Curie, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Unité INSERM U830, Institut Curie, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><country xml:lang="fr">France</country><wicri:regionArea>Université Paris Descartes, Faculté de Médecine, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation></author><author><name sortKey="Caux Oncoutier, Virginie" sort="Caux Oncoutier, Virginie" uniqKey="Caux Oncoutier V" first="Virginie" last="Caux-Moncoutier">Virginie Caux-Moncoutier</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Génétique Oncologique, Institut Curie, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="De Pauw, Antoine" sort="De Pauw, Antoine" uniqKey="De Pauw A" first="Antoine" last="De Pauw">Antoine De Pauw</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Génétique Oncologique, Institut Curie, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Gauthier Illars, Marion" sort="Gauthier Illars, Marion" uniqKey="Gauthier Illars M" first="Marion" last="Gauthier-Villars">Marion Gauthier-Villars</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Génétique Oncologique, Institut Curie, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Leone, Melanie" sort="Leone, Melanie" uniqKey="Leone M" first="Mélanie" last="Léoné">Mélanie Léoné</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Centre Hospitalier Universitaire de Lyon / Centre Léon Bérard, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Calender, Alain" sort="Calender, Alain" uniqKey="Calender A" first="Alain" last="Calender">Alain Calender</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Centre Hospitalier Universitaire de Lyon / Centre Léon Bérard, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Université Lyon 1, CNRS UMR5558, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bonadona, Valerie" sort="Bonadona, Valerie" uniqKey="Bonadona V" first="Valérie" last="Bonadona">Valérie Bonadona</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Université Lyon 1, CNRS UMR5558, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Hardouin, Agnes" sort="Hardouin, Agnes" uniqKey="Hardouin A" first="Agnès" last="Hardouin">Agnès Hardouin</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Centre François Baclesse, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="Berthet, Pascaline" sort="Berthet, Pascaline" uniqKey="Berthet P" first="Pascaline" last="Berthet">Pascaline Berthet</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Centre François Baclesse, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="Bignon, Yves Ean" sort="Bignon, Yves Ean" uniqKey="Bignon Y" first="Yves-Jean" last="Bignon">Yves-Jean Bignon</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Département d'Oncogénétique, Centre Jean Perrin, Université d'Auvergne, Auvergne</wicri:regionArea><wicri:noRegion>Auvergne</wicri:noRegion><wicri:noRegion>Auvergne</wicri:noRegion></affiliation></author><author><name sortKey="Uhrhammer, Nancy" sort="Uhrhammer, Nancy" uniqKey="Uhrhammer N" first="Nancy" last="Uhrhammer">Nancy Uhrhammer</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Département d'Oncogénétique, Centre Jean Perrin, Université d'Auvergne, Auvergne</wicri:regionArea><wicri:noRegion>Auvergne</wicri:noRegion><wicri:noRegion>Auvergne</wicri:noRegion></affiliation></author><author><name sortKey="Faivre, Laurence" sort="Faivre, Laurence" uniqKey="Faivre L" first="Laurence" last="Faivre">Laurence Faivre</name><affiliation wicri:level="4"><country xml:lang="fr">France</country><wicri:regionArea>Centre de Génétique, CHU Dijon, Université de Bourgogne, Dijon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Bourgogne</region><settlement type="city">Dijon</settlement><settlement type="city">Dijon</settlement></placeName><orgName type="university">Université de Bourgogne</orgName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Centre Georges François Leclerc, Dijon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Bourgogne</region><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Loustalot, Catherine" sort="Loustalot, Catherine" uniqKey="Loustalot C" first="Catherine" last="Loustalot">Catherine Loustalot</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Centre Georges François Leclerc, Dijon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Bourgogne</region><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Buys, Saundra" sort="Buys, Saundra" uniqKey="Buys S" first="Saundra" last="Buys">Saundra Buys</name><affiliation><wicri:noCountry code="subField">City</wicri:noCountry></affiliation></author><author><name sortKey="Daly, Mary" sort="Daly, Mary" uniqKey="Daly M" first="Mary" last="Daly">Mary Daly</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Fox Chase Cancer Center, Philadelphia</wicri:cityArea></affiliation></author><author><name sortKey="Miron, Alex" sort="Miron, Alex" uniqKey="Miron A" first="Alex" last="Miron">Alex Miron</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Cancer Biology, Dana‐Farber Cancer Institute, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Beth Terry, Mary" sort="Beth Terry, Mary" uniqKey="Beth Terry M" first="Mary" last="Beth Terry">Mary Beth Terry</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Epidemiology, Columbia University, New York</wicri:cityArea></affiliation></author><author><name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K." last="Chung">Wendy K. Chung</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Epidemiology, Columbia University, New York</wicri:cityArea></affiliation></author><author><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M" last="John">Esther M. John</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Epidemiology, Cancer Prevention Institute of California, Fremont</wicri:cityArea></affiliation></author><author><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name><affiliation wicri:level="4"><country xml:lang="fr">Australie</country><wicri:regionArea>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Goldgar, David" sort="Goldgar, David" uniqKey="Goldgar D" first="David" last="Goldgar">David Goldgar</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Utah</region></placeName><wicri:cityArea>Department of Dermatology, University of Utah School of Medicine, Salt Lake City</wicri:cityArea></affiliation></author><author><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F." last="Singer">Christian F. Singer</name><affiliation wicri:level="3"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Austria, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Tea, Muy Heng" sort="Tea, Muy Heng" uniqKey="Tea M" first="Muy-Kheng" last="Tea">Muy-Kheng Tea</name><affiliation wicri:level="3"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Austria, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Pfeiler, Georg" sort="Pfeiler, Georg" uniqKey="Pfeiler G" first="Georg" last="Pfeiler">Georg Pfeiler</name><affiliation wicri:level="3"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Austria, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Fink Etter, Anneliese" sort="Fink Etter, Anneliese" uniqKey="Fink Etter A" first="Anneliese" last="Fink-Retter">Anneliese Fink-Retter</name><affiliation wicri:level="3"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of OB/GYN and Comprehensive Cancer Center, Medical University of Austria, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><affiliation wicri:level="3"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Johannsson, Oskar Th" sort="Johannsson, Oskar Th" uniqKey="Johannsson O" first="Oskar Th." last="Johannsson">Oskar Th. Johannsson</name><affiliation wicri:level="1"><country xml:lang="fr">Islande</country><wicri:regionArea>Department of Oncology, Landspitali University Hospital, Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Clinical Cancer Genetics Laboratory, Memorial Sloane Kettering Cancer Center, New York</wicri:cityArea></affiliation></author><author><name sortKey="Kirchhoff, Tomas" sort="Kirchhoff, Tomas" uniqKey="Kirchhoff T" first="Tomas" last="Kirchhoff">Tomas Kirchhoff</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Environmental Medicine, NYU Cancer Institute, New York University School of Medicine, New York</wicri:cityArea></affiliation></author><author><name sortKey="Gaudet, Mia M" sort="Gaudet, Mia M" uniqKey="Gaudet M" first="Mia M." last="Gaudet">Mia M. Gaudet</name><affiliation wicri:level="1"><country xml:lang="fr">Géorgie (pays)</country><wicri:regionArea>Epidemiology Research Program, American Cancer Society, Atlanta</wicri:regionArea><wicri:noRegion>Atlanta</wicri:noRegion></affiliation></author><author><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Clinical Cancer Genetics Laboratory, Memorial Sloane Kettering Cancer Center, New York</wicri:cityArea></affiliation></author><author><name sortKey="Robson, Mark" sort="Robson, Mark" uniqKey="Robson M" first="Mark" last="Robson">Mark Robson</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Memorial Sloan‐Kettering Cancer Center, New York</wicri:cityArea></affiliation></author><author><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo</wicri:cityArea></affiliation></author><author><name sortKey="Phillips, Kelly Nne" sort="Phillips, Kelly Nne" uniqKey="Phillips K" first="Kelly-Anne" last="Phillips">Kelly-Anne Phillips</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne</wicri:regionArea><wicri:noRegion>East Melbourne</wicri:noRegion></affiliation></author><author><name sortKey="Van Le, Linda" sort="Van Le, Linda" uniqKey="Van Le L" first="Linda" last="Van Le">Linda Van Le</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Gynecologic Oncology Group, University of North Carolina at Chapel Hill, Chapel Hill</wicri:cityArea></affiliation></author><author><name sortKey="Hoffman, James S" sort="Hoffman, James S" uniqKey="Hoffman J" first="James S" last="Hoffman">James S. Hoffman</name><affiliation><wicri:noCountry code="subField">Conneticut</wicri:noCountry></affiliation></author><author><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Divison of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus</wicri:cityArea></affiliation></author><author><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV ‐ IRCCS, Padua</wicri:regionArea><wicri:noRegion>Padua</wicri:noRegion></affiliation></author><author><name sortKey="Tognazzo, Silvia" sort="Tognazzo, Silvia" uniqKey="Tognazzo S" first="Silvia" last="Tognazzo">Silvia Tognazzo</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV ‐ IRCCS, Padua</wicri:regionArea><wicri:noRegion>Padua</wicri:noRegion></affiliation></author><author><name sortKey="Imyanitov, Evgeny" sort="Imyanitov, Evgeny" uniqKey="Imyanitov E" first="Evgeny" last="Imyanitov">Evgeny Imyanitov</name><affiliation wicri:level="1"><country xml:lang="fr">Russie</country><wicri:regionArea>Laboratory of Molecular Oncology, N.N. Petrov Institute of Oncology, St.‐Petersburg</wicri:regionArea><wicri:noRegion>St.‐Petersburg</wicri:noRegion></affiliation></author><author><name sortKey="Isaacs, Claudine" sort="Isaacs, Claudine" uniqKey="Isaacs C" first="Claudine" last="Isaacs">Claudine Isaacs</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">Washington (district de Columbia)</settlement><region type="state">District de Columbia</region></placeName><wicri:orgArea>Lombardi Comprehensive Cancer Center, Georgetown University</wicri:orgArea></affiliation></author><author><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name><affiliation wicri:level="1"><country xml:lang="fr">Lituanie</country><wicri:regionArea>Vilnius University Hospital Santariskiu Clinics, Hematology, Oncology and Transfusion Medicine Center, Department of Molecular and Regenerative Medicine; State Research Institute Inovative Medicine Center, Vilnius</wicri:regionArea><wicri:noRegion>Vilnius</wicri:noRegion></affiliation></author><author><name sortKey="Lazaro, Conxi" sort="Lazaro, Conxi" uniqKey="Lazaro C" first="Conxi" last="Lazaro">Conxi Lazaro</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Molecular Diagnostic Unit, Hereditari Cancer Program, IDIBELL‐Catalan Institute of Oncology, Catalanes</wicri:regionArea><wicri:noRegion>Catalanes</wicri:noRegion></affiliation></author><author><name sortKey="Blanco, Ignacio" sort="Blanco, Ignacio" uniqKey="Blanco I" first="Ignacio" last="Blanco">Ignacio Blanco</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Genetic Counseling Unit, Hereditari Cancer Program, IDIBELL‐Catalan Institute of Oncology, Catalanes</wicri:regionArea><wicri:noRegion>Catalanes</wicri:noRegion></affiliation></author><author><name sortKey="Tornero, Eva" sort="Tornero, Eva" uniqKey="Tornero E" first="Eva" last="Tornero">Eva Tornero</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Molecular Diagnostic Unit, Hereditari Cancer Program, IDIBELL‐Catalan Institute of Oncology, Catalanes</wicri:regionArea><wicri:noRegion>Catalanes</wicri:noRegion></affiliation></author><author><name sortKey="Navarro, Matilde" sort="Navarro, Matilde" uniqKey="Navarro M" first="Matilde" last="Navarro">Matilde Navarro</name><affiliation wicri:level="1"><country xml:lang="fr">Espagne</country><wicri:regionArea>Genetic Counseling Unit, Hereditari Cancer Program, IDIBELL‐Catalan Institute of Oncology, Catalanes</wicri:regionArea><wicri:noRegion>Catalanes</wicri:noRegion></affiliation></author><author><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B." last="Moysich">Kirsten B. Moysich</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo</wicri:cityArea></affiliation></author><author><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars‐Sinai Medical Center, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Gross, Jenny" sort="Gross, Jenny" uniqKey="Gross J" first="Jenny" last="Gross">Jenny Gross</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars‐Sinai Medical Center, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name><affiliation wicri:level="3"><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Molecular Genetics, National Institute of Oncology, Budapest</wicri:regionArea><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Vaszko, Tibor" sort="Vaszko, Tibor" uniqKey="Vaszko T" first="Tibor" last="Vaszko">Tibor Vaszko</name><affiliation wicri:level="3"><country xml:lang="fr">Hongrie</country><wicri:regionArea>Department of Molecular Genetics, National Institute of Oncology, Budapest</wicri:regionArea><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Teo, Soo Wang" sort="Teo, Soo Wang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name><affiliation wicri:level="1"><country xml:lang="fr">Malaisie</country><wicri:regionArea>Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Malaysia and University Malaya Cancer Research Institute, University Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Ganz, Patricia A" sort="Ganz, Patricia A" uniqKey="Ganz P" first="Patricia A." last="Ganz">Patricia A. Ganz</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>UCLA Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Center, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Beattie, Mary S" sort="Beattie, Mary S" uniqKey="Beattie M" first="Mary S." last="Beattie">Mary S. Beattie</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>University of California, San Francisco, Departments of Medicine, Epidemiology, and Biostatistics, San Francisco</wicri:cityArea></affiliation></author><author><name sortKey="Dorfling, Cecelia M" sort="Dorfling, Cecelia M" uniqKey="Dorfling C" first="Cecelia M" last="Dorfling">Cecelia M. Dorfling</name><affiliation wicri:level="1"><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Pretoria</wicri:regionArea><wicri:noRegion>Pretoria</wicri:noRegion></affiliation></author><author><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J." last="Van Rensburg">Elizabeth J. Van Rensburg</name><affiliation wicri:level="1"><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Pretoria</wicri:regionArea><wicri:noRegion>Pretoria</wicri:noRegion></affiliation></author><author><name sortKey="Diez, Orland" sort="Diez, Orland" uniqKey="Diez O" first="Orland" last="Diez">Orland Diez</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Oncogenetics Laboratory. Vall d'Hebron Institute of Oncology (VHIO); University Hospital Vall d'Hebron, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Kwong, Ava" sort="Kwong, Ava" uniqKey="Kwong A" first="Ava" last="Kwong">Ava Kwong</name><affiliation wicri:level="1"><country xml:lang="fr">Hong Kong</country><wicri:regionArea>The Hong Kong Hereditary Breast Cancer Family Registry; Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong; Department of Surgery, The University of Hong Kong, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Centre of Familial Breast and Ovarian Cancer, Department of Gynaecology and Obstetrics and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Ditsch, Nina" sort="Ditsch, Nina" uniqKey="Ditsch N" first="Nina" last="Ditsch">Nina Ditsch</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, Ludwig‐Maximilian University Munich, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital of Schleswig‐Holstein, Campus Kiel, Christian‐Albrechts University Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Heidemann, Simone" sort="Heidemann, Simone" uniqKey="Heidemann S" first="Simone" last="Heidemann">Simone Heidemann</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University Hospital of Schleswig‐Holstein, Campus Kiel, Christian‐Albrechts University Kiel, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Niederacher, Dieter" sort="Niederacher, Dieter" uniqKey="Niederacher D" first="Dieter" last="Niederacher">Dieter Niederacher</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich‐Heine University Düsseldorf, Dusseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Preisler Dams, Sabine" sort="Preisler Dams, Sabine" uniqKey="Preisler Dams S" first="Sabine" last="Preisler-Adams">Sabine Preisler-Adams</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Münster, Münster</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Münster</region><settlement type="city">Münster</settlement></placeName></affiliation></author><author><name sortKey="Gadzicki, Dorotehea" sort="Gadzicki, Dorotehea" uniqKey="Gadzicki D" first="Dorotehea" last="Gadzicki">Dorotehea Gadzicki</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Varon Ateeva, Raymonda" sort="Varon Ateeva, Raymonda" uniqKey="Varon Ateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin</wicri:regionArea><wicri:noRegion>Charite Berlin</wicri:noRegion><wicri:noRegion>Charite Berlin</wicri:noRegion></affiliation></author><author><name sortKey="Deissler, Helmut" sort="Deissler, Helmut" uniqKey="Deissler H" first="Helmut" last="Deissler">Helmut Deissler</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName></affiliation></author><author><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Wuzburg</wicri:regionArea><wicri:noRegion>Wuzburg</wicri:noRegion><wicri:noRegion>Wuzburg</wicri:noRegion></affiliation></author><author><name sortKey="Sutter, Christian" sort="Sutter, Christian" uniqKey="Sutter C" first="Christian" last="Sutter">Christian Sutter</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Kast, Karin" sort="Kast, Karin" uniqKey="Kast K" first="Karin" last="Kast">Karin Kast</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Fiebig, Britta" sort="Fiebig, Britta" uniqKey="Fiebig B" first="Britta" last="Fiebig">Britta Fiebig</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Sch Fer, Dieter" sort="Sch Fer, Dieter" uniqKey="Sch Fer D" first="Dieter" last="Sch Fer">Dieter Sch Fer</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University Hospital Frankfurt a.M., Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Caldes, Trinidad" sort="Caldes, Trinidad" uniqKey="Caldes T" first="Trinidad" last="Caldes">Trinidad Caldes</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Molecular Oncology Laboratory, Hospital Clinico San Carlos, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="De La Hoya, Miguel" sort="De La Hoya, Miguel" uniqKey="De La Hoya M" first="Miguel" last="De La Hoya">Miguel De La Hoya</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Molecular Oncology Laboratory, Hospital Clinico San Carlos, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name><affiliation wicri:level="1"><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Plante, Marie" sort="Plante, Marie" uniqKey="Plante M" first="Marie" last="Plante">Marie Plante</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Gynaecologic Oncology Service, Centre Hospitalier Universitaire de Québec (CHUQ), Côte du Palais, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Genetics and Population Health Division, Queensland Institute of Medical Research, Herston</wicri:regionArea><wicri:noRegion>Herston</wicri:noRegion></affiliation></author><author><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L." last="Neuhausen">Susan L. Neuhausen</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte</wicri:cityArea></affiliation></author><author><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Lindor, Noralane" sort="Lindor, Noralane" uniqKey="Lindor N" first="Noralane" last="Lindor">Noralane Lindor</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Medical Genetics, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Pankratz, V Shane" sort="Pankratz, V Shane" uniqKey="Pankratz V" first="V. Shane" last="Pankratz">V. Shane Pankratz</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Health Sciences Research, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Zaffaroni, Daniela" sort="Zaffaroni, Daniela" uniqKey="Zaffaroni D" first="Daniela" last="Zaffaroni">Daniela Zaffaroni</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia (IEO), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Experimental Oncology, Istituto Europeo di Oncologia, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Consortium for Genomics Technology (Cogentech), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Cancer Bioimmunotherapy Unit, Centro di Riferimento Oncologico, IRCCS, Aviano (PN)</wicri:regionArea><wicri:noRegion>Aviano (PN)</wicri:noRegion></affiliation></author><author><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics Unit, Department of Clinical Physiopathology, University of Florence, Firenze</wicri:regionArea><wicri:noRegion>Firenze</wicri:noRegion></affiliation></author><author><name sortKey="Ottini, Laura" sort="Ottini, Laura" uniqKey="Ottini L" first="Laura" last="Ottini">Laura Ottini</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Medicine, “Sapienza” University of Rome, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predicted Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H." last="Greene">Mark H. Greene</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L." last="Mai">Phuong L. Mai</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville</wicri:cityArea></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1×5, Cancer Care Ontario, Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Cancer Genetics Network: Cancer Care Ontario, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Ozcelik, Hilmi" sort="Ozcelik, Hilmi" uniqKey="Ozcelik H" first="Hilmi" last="Ozcelik">Hilmi Ozcelik</name><affiliation wicri:level="4"><country xml:lang="fr">Canada</country><wicri:regionArea>Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1×5, Cancer Care Ontario, Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Gayther, Simon A" sort="Gayther, Simon A" uniqKey="Gayther S" first="Simon A." last="Gayther">Simon A. Gayther</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California</wicri:cityArea></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City</wicri:regionArea><wicri:noRegion>Quebec City</wicri:noRegion></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Center for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Chenevix Rench, Georgia" sort="Chenevix Rench, Georgia" uniqKey="Chenevix Rench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Genetics and Population Health Division, Queensland Institute of Medical Research, Herston</wicri:regionArea><wicri:noRegion>Herston</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Human Mutation</title><title level="j" type="sub">Focus on the NIH Undiagnosed Diseases Program</title><title level="j" type="alt">HUMAN MUTATION</title><idno type="ISSN">1059-7794</idno><idno type="eISSN">1098-1004</idno><imprint><biblScope unit="vol">33</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="690">690</biblScope><biblScope unit="page" to="702">702</biblScope><biblScope unit="page-count">13</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-04">2012-04</date></imprint><idno type="ISSN">1059-7794</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1059-7794</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Allele</term><term>Allele brca1</term><term>Allele brca2</term><term>Antoniou</term><term>Association study</term><term>Brca1</term><term>Brca1 brca2 mutation carriers</term><term>Brca1 carriers</term><term>Brca1 mutation carriers</term><term>Brca2</term><term>Brca2 carriers</term><term>Brca2 mutation carriers</term><term>Brca2 mutations</term><term>Breast</term><term>Breast cancer</term><term>Breast cancer family registry</term><term>Breast cancer linkage consortium</term><term>Breast cancer research foundation</term><term>Breast cancer risk</term><term>Cancer</term><term>Cancer care ontario</term><term>Cancer center</term><term>Cancer genetics network</term><term>Cancer institute</term><term>Cancer prevention</term><term>Cancer research</term><term>Cancer risk</term><term>Carrier</term><term>Centre</term><term>Centre hospitalier universitaire</term><term>Chase cancer center</term><term>Cimba</term><term>Clinical genetics</term><term>Common variants</term><term>Consortium</term><term>Easton</term><term>Epidemiology</term><term>Familial breast cancer</term><term>Fondazione</term><term>Fondazione irccs istituto nazionale tumori</term><term>Foundation trust</term><term>General population</term><term>Genet</term><term>Genet antoniou</term><term>Genetics</term><term>Genetics service</term><term>Genotype</term><term>Genotyping</term><term>Gilda radner</term><term>Grant number</term><term>Gwas</term><term>Gynaecology</term><term>Gynecologic oncology group</term><term>Healey</term><term>Helsinki</term><term>Helsinki university</term><term>Hereditary breast</term><term>Hong kong</term><term>Human genetics</term><term>Human mutation</term><term>Istituto</term><term>Istituto europeo</term><term>Karolinska university hospital</term><term>Laboratory medicine</term><term>Locus</term><term>Lund university hospital</term><term>Many others</term><term>Mayo clinic</term><term>Medical genetics</term><term>Milan</term><term>Ministero della salute</term><term>Minor allele</term><term>Molecular genetics</term><term>Molecular medicine</term><term>Mutation</term><term>Mutation carriers</term><term>National cancer institute</term><term>National institutes</term><term>Netherlands</term><term>Netherlands cancer institute</term><term>Obstetrics</term><term>Ohio state university</term><term>Oncology</term><term>Ontario</term><term>Ontario cancer genetics network</term><term>Ovarian</term><term>Ovarian cancer</term><term>Ovarian cancer cases</term><term>Ovarian cancer gwas</term><term>Ovarian cancer risk</term><term>Primary analysis</term><term>Primary care</term><term>Principal research fellow</term><term>Public health</term><term>Ramus</term><term>Royal marsden</term><term>Senior cancer research fellow</term><term>Sinilnikova</term><term>Snp</term><term>Susceptibility</term><term>Technical support</term><term>Tumori</term><term>University hospital</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Allele</term><term>Allele brca1</term><term>Allele brca2</term><term>Antoniou</term><term>Association study</term><term>Brca1</term><term>Brca1 brca2 mutation carriers</term><term>Brca1 carriers</term><term>Brca1 mutation carriers</term><term>Brca2</term><term>Brca2 carriers</term><term>Brca2 mutation carriers</term><term>Brca2 mutations</term><term>Breast</term><term>Breast cancer</term><term>Breast cancer family registry</term><term>Breast cancer linkage consortium</term><term>Breast cancer research foundation</term><term>Breast cancer risk</term><term>Cancer</term><term>Cancer care ontario</term><term>Cancer center</term><term>Cancer genetics network</term><term>Cancer institute</term><term>Cancer prevention</term><term>Cancer research</term><term>Cancer risk</term><term>Carrier</term><term>Centre</term><term>Centre hospitalier universitaire</term><term>Chase cancer center</term><term>Cimba</term><term>Clinical genetics</term><term>Common variants</term><term>Consortium</term><term>Easton</term><term>Epidemiology</term><term>Familial breast cancer</term><term>Fondazione</term><term>Fondazione irccs istituto nazionale tumori</term><term>Foundation trust</term><term>General population</term><term>Genet</term><term>Genet antoniou</term><term>Genetics</term><term>Genetics service</term><term>Genotype</term><term>Genotyping</term><term>Gilda radner</term><term>Grant number</term><term>Gwas</term><term>Gynaecology</term><term>Gynecologic oncology group</term><term>Healey</term><term>Helsinki</term><term>Helsinki university</term><term>Hereditary breast</term><term>Hong kong</term><term>Human genetics</term><term>Human mutation</term><term>Istituto</term><term>Istituto europeo</term><term>Karolinska university hospital</term><term>Laboratory medicine</term><term>Locus</term><term>Lund university hospital</term><term>Many others</term><term>Mayo clinic</term><term>Medical genetics</term><term>Milan</term><term>Ministero della salute</term><term>Minor allele</term><term>Molecular genetics</term><term>Molecular medicine</term><term>Mutation</term><term>Mutation carriers</term><term>National cancer institute</term><term>National institutes</term><term>Netherlands</term><term>Netherlands cancer institute</term><term>Obstetrics</term><term>Ohio state university</term><term>Oncology</term><term>Ontario</term><term>Ontario cancer genetics network</term><term>Ovarian</term><term>Ovarian cancer</term><term>Ovarian cancer cases</term><term>Ovarian cancer gwas</term><term>Ovarian cancer risk</term><term>Primary analysis</term><term>Primary care</term><term>Principal research fellow</term><term>Public health</term><term>Ramus</term><term>Royal marsden</term><term>Senior cancer research fellow</term><term>Sinilnikova</term><term>Snp</term><term>Susceptibility</term><term>Technical support</term><term>Tumori</term><term>University hospital</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Pays-Bas</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Cancer</term><term>Transporteur</term><term>Consortium</term><term>épidémiologie</term><term>Génétique</term><term>Gynécologie</term><term>Santé publique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome‐wide association study (GWAS) identified six alleles associated with risk of ovarian cancer for women in the general population. We evaluated four of these loci as potential modifiers of ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Four single‐nucleotide polymorphisms (SNPs), rs10088218 (at 8q24), rs2665390 (at 3q25), rs717852 (at 2q31), and rs9303542 (at 17q21), were genotyped in 12,599 BRCA1 and 7,132 BRCA2 carriers, including 2,678 ovarian cancer cases. Associations were evaluated within a retrospective cohort approach. All four loci were associated with ovarian cancer risk in BRCA2 carriers; rs10088218 per‐allele hazard ratio (HR) = 0.81 (95% CI: 0.67–0.98) P‐trend = 0.033, rs2665390 HR = 1.48 (95% CI: 1.21–1.83) P‐trend = 1.8 × 10−4, rs717852 HR = 1.25 (95% CI: 1.10–1.42) P‐trend = 6.6 × 10−4, rs9303542 HR = 1.16 (95% CI: 1.02–1.33) P‐trend = 0.026. Two loci were associated with ovarian cancer risk in BRCA1 carriers; rs10088218 per‐allele HR = 0.89 (95% CI: 0.81–0.99) P‐trend = 0.029, rs2665390 HR = 1.25 (95% CI: 1.10–1.42) P‐trend = 6.1 × 10−4. The HR estimates for the remaining loci were consistent with odds ratio estimates for the general population. The identification of multiple loci modifying ovarian cancer risk may be useful for counseling women with BRCA1 and BRCA2 mutations regarding their risk of ovarian cancer. Hum Mutat 33:690–702, 2012. © 2012 Wiley Periodicals, Inc.</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Canada</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Géorgie (pays)</li><li>Hong Kong</li><li>Hongrie</li><li>Irlande (pays)</li><li>Islande</li><li>Italie</li><li>Lituanie</li><li>Malaisie</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>Russie</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Auvergne-Rhône-Alpes</li><li>Bade-Wurtemberg</li><li>Basse-Normandie</li><li>Basse-Saxe</li><li>Bavière</li><li>Bourgogne</li><li>Bourgogne-Franche-Comté</li><li>Californie</li><li>Caroline du Nord</li><li>Catalogne</li><li>Communauté de Madrid</li><li>District de Columbia</li><li>District de Darmstadt</li><li>District de Dresde</li><li>District de Düsseldorf</li><li>District de Haute-Bavière</li><li>District de Karlsruhe</li><li>District de Leipzig</li><li>District de Münster</li><li>District de Tübingen</li><li>Grand Londres</li><li>Grand Manchester</li><li>Gueldre</li><li>Hesse (Land)</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Hongrie centrale</li><li>Hovedstaden</li><li>Kansas</li><li>Latium</li><li>Lombardie</li><li>Maryland</li><li>Massachusetts</li><li>Midlands de l'Ouest</li><li>Minnesota</li><li>Ohio</li><li>Ontario</li><li>Oxfordshire</li><li>Pennsylvanie</li><li>Rhénanie-du-Nord-Westphalie</li><li>Rhône-Alpes</li><li>Région Normandie</li><li>Saxe (Land)</li><li>Schleswig-Holstein</li><li>Svealand</li><li>Toscane</li><li>Utah</li><li>Victoria (État)</li><li>Vienne (Autriche)</li><li>Écosse</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Amsterdam</li><li>Barcelone</li><li>Birmingham</li><li>Budapest</li><li>Caen</li><li>Cambridge</li><li>Copenhague</li><li>Dijon</li><li>Dresde</li><li>Düsseldorf</li><li>Francfort-sur-le-Main</li><li>Hanovre</li><li>Heidelberg</li><li>Kiel</li><li>Leipzig</li><li>Leyde</li><li>Londres</li><li>Lyon</li><li>Madrid</li><li>Manchester</li><li>Melbourne</li><li>Milan</li><li>Munich</li><li>Münster</li><li>Nimègue</li><li>Oxford</li><li>Paris</li><li>Pise</li><li>Rome</li><li>Rotterdam</li><li>Stockholm</li><li>Toronto</li><li>Ulm</li><li>Vienne (Autriche)</li><li>Washington (district de Columbia)</li><li>Édimbourg</li></settlement><orgName><li>Université Paris-Descartes</li><li>Université de Bourgogne</li><li>Université de Cambridge</li><li>Université de Londres</li><li>Université de Melbourne</li><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Buys, Saundra" sort="Buys, Saundra" uniqKey="Buys S" first="Saundra" last="Buys">Saundra Buys</name><name sortKey="Hoffman, James S" sort="Hoffman, James S" uniqKey="Hoffman J" first="James S" last="Hoffman">James S. Hoffman</name></noCountry><country name="États-Unis"><region name="Californie"><name sortKey="Ramus, Susan J" sort="Ramus, Susan J" uniqKey="Ramus S" first="Susan J." last="Ramus">Susan J. Ramus</name></region><name sortKey="Beattie, Mary S" sort="Beattie, Mary S" uniqKey="Beattie M" first="Mary S." last="Beattie">Mary S. Beattie</name><name sortKey="Beth Terry, Mary" sort="Beth Terry, Mary" uniqKey="Beth Terry M" first="Mary" last="Beth Terry">Mary Beth Terry</name><name sortKey="Chung, Wendy K" sort="Chung, Wendy K" uniqKey="Chung W" first="Wendy K." last="Chung">Wendy K. Chung</name><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><name sortKey="Daly, Mary" sort="Daly, Mary" uniqKey="Daly M" first="Mary" last="Daly">Mary Daly</name><name sortKey="Ding, Yuan Chun" sort="Ding, Yuan Chun" uniqKey="Ding Y" first="Yuan Chun" last="Ding">Yuan Chun Ding</name><name sortKey="Domchek, Susan M" sort="Domchek, Susan M" uniqKey="Domchek S" first="Susan M." last="Domchek">Susan M. Domchek</name><name sortKey="Fredericksen, Zachary" sort="Fredericksen, Zachary" uniqKey="Fredericksen Z" first="Zachary" last="Fredericksen">Zachary Fredericksen</name><name sortKey="Ganz, Patricia A" sort="Ganz, Patricia A" uniqKey="Ganz P" first="Patricia A." last="Ganz">Patricia A. Ganz</name><name sortKey="Gayther, Simon A" sort="Gayther, Simon A" uniqKey="Gayther S" first="Simon A." last="Gayther">Simon A. Gayther</name><name sortKey="Godwin, Andrew K" sort="Godwin, Andrew K" uniqKey="Godwin A" first="Andrew K." last="Godwin">Andrew K. Godwin</name><name sortKey="Goldgar, David" sort="Goldgar, David" uniqKey="Goldgar D" first="David" last="Goldgar">David Goldgar</name><name sortKey="Greene, Mark H" sort="Greene, Mark H" uniqKey="Greene M" first="Mark H." last="Greene">Mark H. Greene</name><name sortKey="Gross, Jenny" sort="Gross, Jenny" uniqKey="Gross J" first="Jenny" last="Gross">Jenny Gross</name><name sortKey="Isaacs, Claudine" sort="Isaacs, Claudine" uniqKey="Isaacs C" first="Claudine" last="Isaacs">Claudine Isaacs</name><name sortKey="John, Esther M" sort="John, Esther M" uniqKey="John E" first="Esther M" last="John">Esther M. John</name><name sortKey="Karlan, Beth Y" sort="Karlan, Beth Y" uniqKey="Karlan B" first="Beth Y." last="Karlan">Beth Y. Karlan</name><name sortKey="Kirchhoff, Tomas" sort="Kirchhoff, Tomas" uniqKey="Kirchhoff T" first="Tomas" last="Kirchhoff">Tomas Kirchhoff</name><name sortKey="Lindor, Noralane" sort="Lindor, Noralane" uniqKey="Lindor N" first="Noralane" last="Lindor">Noralane Lindor</name><name sortKey="Mai, Phuong L" sort="Mai, Phuong L" uniqKey="Mai P" first="Phuong L." last="Mai">Phuong L. Mai</name><name sortKey="Miron, Alex" sort="Miron, Alex" uniqKey="Miron A" first="Alex" last="Miron">Alex Miron</name><name sortKey="Moysich, Kirsten B" sort="Moysich, Kirsten B" uniqKey="Moysich K" first="Kirsten B." last="Moysich">Kirsten B. Moysich</name><name sortKey="Nathanson, Katherine L" sort="Nathanson, Katherine L" uniqKey="Nathanson K" first="Katherine L." last="Nathanson">Katherine L. Nathanson</name><name sortKey="Neuhausen, Susan L" sort="Neuhausen, Susan L" uniqKey="Neuhausen S" first="Susan L." last="Neuhausen">Susan L. Neuhausen</name><name sortKey="Offit, Kenneth" sort="Offit, Kenneth" uniqKey="Offit K" first="Kenneth" last="Offit">Kenneth Offit</name><name sortKey="Pankratz, V Shane" sort="Pankratz, V Shane" uniqKey="Pankratz V" first="V. Shane" last="Pankratz">V. Shane Pankratz</name><name sortKey="Pathak, Harsh" sort="Pathak, Harsh" uniqKey="Pathak H" first="Harsh" last="Pathak">Harsh Pathak</name><name sortKey="Piedmonte, Marion" sort="Piedmonte, Marion" uniqKey="Piedmonte M" first="Marion" last="Piedmonte">Marion Piedmonte</name><name sortKey="Rebbeck, Timothy R" sort="Rebbeck, Timothy R" uniqKey="Rebbeck T" first="Timothy R." last="Rebbeck">Timothy R. Rebbeck</name><name sortKey="Robson, Mark" sort="Robson, Mark" uniqKey="Robson M" first="Mark" last="Robson">Mark Robson</name><name sortKey="Toland, Amanda Ewart" sort="Toland, Amanda Ewart" uniqKey="Toland A" first="Amanda Ewart" last="Toland">Amanda Ewart Toland</name><name sortKey="Van Le, Linda" sort="Van Le, Linda" uniqKey="Van Le L" first="Linda" last="Van Le">Linda Van Le</name><name sortKey="Vijai, Joseph" sort="Vijai, Joseph" uniqKey="Vijai J" first="Joseph" last="Vijai">Joseph Vijai</name><name sortKey="Wang, Xianshu" sort="Wang, Xianshu" uniqKey="Wang X" first="Xianshu" last="Wang">Xianshu Wang</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name></region><name sortKey="Adlard, Julian" sort="Adlard, Julian" uniqKey="Adlard J" first="Julian" last="Adlard">Julian Adlard</name><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name><name sortKey="Barrowdale, Daniel" sort="Barrowdale, Daniel" uniqKey="Barrowdale D" first="Daniel" last="Barrowdale">Daniel Barrowdale</name><name sortKey="Brewer, Carole" sort="Brewer, Carole" uniqKey="Brewer C" first="Carole" last="Brewer">Carole Brewer</name><name sortKey="Cole, Trevor" sort="Cole, Trevor" uniqKey="Cole T" first="Trevor" last="Cole">Trevor Cole</name><name sortKey="Cook, Jackie" sort="Cook, Jackie" uniqKey="Cook J" first="Jackie" last="Cook">Jackie Cook</name><name sortKey="Davidson, Rosemarie" sort="Davidson, Rosemarie" uniqKey="Davidson R" first="Rosemarie" last="Davidson">Rosemarie Davidson</name><name sortKey="Douglas, Fiona" sort="Douglas, Fiona" uniqKey="Douglas F" first="Fiona" last="Douglas">Fiona Douglas</name><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><name sortKey="Eccles, Diana" sort="Eccles, Diana" uniqKey="Eccles D" first="Diana" last="Eccles">Diana Eccles</name><name sortKey="Eeles, Ros" sort="Eeles, Ros" uniqKey="Eeles R" first="Ros" last="Eeles">Ros Eeles</name><name sortKey="Ellis, Steve D" sort="Ellis, Steve D" uniqKey="Ellis S" first="Steve D." last="Ellis">Steve D. Ellis</name><name sortKey="Evans, D Gareth" sort="Evans, D Gareth" uniqKey="Evans D" first="D. Gareth" last="Evans">D. Gareth Evans</name><name sortKey="Fineberg, Elena" sort="Fineberg, Elena" uniqKey="Fineberg E" first="Elena" last="Fineberg">Elena Fineberg</name><name sortKey="Frost, Debra" sort="Frost, Debra" uniqKey="Frost D" first="Debra" last="Frost">Debra Frost</name><name sortKey="Hodgson, Shirley" sort="Hodgson, Shirley" uniqKey="Hodgson S" first="Shirley" last="Hodgson">Shirley Hodgson</name><name sortKey="Jacobs, Chris" sort="Jacobs, Chris" uniqKey="Jacobs C" first="Chris" last="Jacobs">Chris Jacobs</name><name sortKey="Kuchenbaecker, Karoline B" sort="Kuchenbaecker, Karoline B" uniqKey="Kuchenbaecker K" first="Karoline B." last="Kuchenbaecker">Karoline B. Kuchenbaecker</name><name sortKey="Lalloo, Fiona" sort="Lalloo, Fiona" uniqKey="Lalloo F" first="Fiona" last="Lalloo">Fiona Lalloo</name><name sortKey="Lee, Andrew" sort="Lee, Andrew" uniqKey="Lee A" first="Andrew" last="Lee">Andrew Lee</name><name sortKey="Mcguffog, Lesley" sort="Mcguffog, Lesley" uniqKey="Mcguffog L" first="Lesley" last="Mcguffog">Lesley Mcguffog</name><name sortKey="Morrison, Patrick J" sort="Morrison, Patrick J" uniqKey="Morrison P" first="Patrick J." last="Morrison">Patrick J. Morrison</name><name sortKey="Paterson, Joan" sort="Paterson, Joan" uniqKey="Paterson J" first="Joan" last="Paterson">Joan Paterson</name><name sortKey="Peock, Susan" sort="Peock, Susan" uniqKey="Peock S" first="Susan" last="Peock">Susan Peock</name><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><name sortKey="Platte, Radka" sort="Platte, Radka" uniqKey="Platte R" first="Radka" last="Platte">Radka Platte</name><name sortKey="Porteous, Mary E" sort="Porteous, Mary E" uniqKey="Porteous M" first="Mary E." last="Porteous">Mary E. Porteous</name><name sortKey="Walker, Lisa" sort="Walker, Lisa" uniqKey="Walker L" first="Lisa" last="Walker">Lisa Walker</name></country><country name="Canada"><noRegion><name sortKey="Soucy, Penny" sort="Soucy, Penny" uniqKey="Soucy P" first="Penny" last="Soucy">Penny Soucy</name></noRegion><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><name sortKey="Glendon, Gord" sort="Glendon, Gord" uniqKey="Glendon G" first="Gord" last="Glendon">Gord Glendon</name><name sortKey="Ozcelik, Hilmi" sort="Ozcelik, Hilmi" uniqKey="Ozcelik H" first="Hilmi" last="Ozcelik">Hilmi Ozcelik</name><name sortKey="Plante, Marie" sort="Plante, Marie" uniqKey="Plante M" first="Marie" last="Plante">Marie Plante</name><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name></country><country name="Australie"><noRegion><name sortKey="Beesley, Jonathan" sort="Beesley, Jonathan" uniqKey="Beesley J" first="Jonathan" last="Beesley">Jonathan Beesley</name></noRegion><name sortKey="Chen, Xiaoqing" sort="Chen, Xiaoqing" uniqKey="Chen X" first="Xiaoqing" last="Chen">Xiaoqing Chen</name><name sortKey="Chenevix Rench, Georgia" sort="Chenevix Rench, Georgia" uniqKey="Chenevix Rench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><name sortKey="Healey, Sue" sort="Healey, Sue" uniqKey="Healey S" first="Sue" last="Healey">Sue Healey</name><name sortKey="Phillips, Kelly Nne" sort="Phillips, Kelly Nne" uniqKey="Phillips K" first="Kelly-Anne" last="Phillips">Kelly-Anne Phillips</name><name sortKey="Southey, Melissa" sort="Southey, Melissa" uniqKey="Southey M" first="Melissa" last="Southey">Melissa Southey</name><name sortKey="Spurdle, Amanda B" sort="Spurdle, Amanda B" uniqKey="Spurdle A" first="Amanda B." last="Spurdle">Amanda B. Spurdle</name></country><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Sinilnikova, Olga M" sort="Sinilnikova, Olga M" uniqKey="Sinilnikova O" first="Olga M." last="Sinilnikova">Olga M. Sinilnikova</name></region><name sortKey="Berthet, Pascaline" sort="Berthet, Pascaline" uniqKey="Berthet P" first="Pascaline" last="Berthet">Pascaline Berthet</name><name sortKey="Bignon, Yves Ean" sort="Bignon, Yves Ean" uniqKey="Bignon Y" first="Yves-Jean" last="Bignon">Yves-Jean Bignon</name><name sortKey="Bonadona, Valerie" sort="Bonadona, Valerie" uniqKey="Bonadona V" first="Valérie" last="Bonadona">Valérie Bonadona</name><name sortKey="Bonadona, Valerie" sort="Bonadona, Valerie" uniqKey="Bonadona V" first="Valérie" last="Bonadona">Valérie Bonadona</name><name sortKey="Calender, Alain" sort="Calender, Alain" uniqKey="Calender A" first="Alain" last="Calender">Alain Calender</name><name sortKey="Caux Oncoutier, Virginie" sort="Caux Oncoutier, Virginie" uniqKey="Caux Oncoutier V" first="Virginie" last="Caux-Moncoutier">Virginie Caux-Moncoutier</name><name sortKey="De Pauw, Antoine" sort="De Pauw, Antoine" uniqKey="De Pauw A" first="Antoine" last="De Pauw">Antoine De Pauw</name><name sortKey="Faivre, Laurence" sort="Faivre, Laurence" uniqKey="Faivre L" first="Laurence" last="Faivre">Laurence Faivre</name><name sortKey="Faivre, Laurence" sort="Faivre, Laurence" uniqKey="Faivre L" first="Laurence" last="Faivre">Laurence Faivre</name><name sortKey="Gauthier Illars, Marion" sort="Gauthier Illars, Marion" uniqKey="Gauthier Illars M" first="Marion" last="Gauthier-Villars">Marion Gauthier-Villars</name><name sortKey="Hardouin, Agnes" sort="Hardouin, Agnes" uniqKey="Hardouin A" first="Agnès" last="Hardouin">Agnès Hardouin</name><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name><name sortKey="Lasset, Christine" sort="Lasset, Christine" uniqKey="Lasset C" first="Christine" last="Lasset">Christine Lasset</name><name sortKey="Leone, Melanie" sort="Leone, Melanie" uniqKey="Leone M" first="Mélanie" last="Léoné">Mélanie Léoné</name><name sortKey="Loustalot, Catherine" sort="Loustalot, Catherine" uniqKey="Loustalot C" first="Catherine" last="Loustalot">Catherine Loustalot</name><name sortKey="Mazoyer, Sylvie" sort="Mazoyer, Sylvie" uniqKey="Mazoyer S" first="Sylvie" last="Mazoyer">Sylvie Mazoyer</name><name sortKey="Sinilnikova, Olga M" sort="Sinilnikova, Olga M" uniqKey="Sinilnikova O" first="Olga M." last="Sinilnikova">Olga M. Sinilnikova</name><name sortKey="Stoppa Yonnet, Dominique" sort="Stoppa Yonnet, Dominique" uniqKey="Stoppa Yonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><name sortKey="Stoppa Yonnet, Dominique" sort="Stoppa Yonnet, Dominique" uniqKey="Stoppa Yonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><name sortKey="Stoppa Yonnet, Dominique" sort="Stoppa Yonnet, Dominique" uniqKey="Stoppa Yonnet D" first="Dominique" last="Stoppa-Lyonnet">Dominique Stoppa-Lyonnet</name><name sortKey="Uhrhammer, Nancy" sort="Uhrhammer, Nancy" uniqKey="Uhrhammer N" first="Nancy" last="Uhrhammer">Nancy Uhrhammer</name></country><country name="Danemark"><noRegion><name sortKey="Thomassen, Mads" sort="Thomassen, Mads" uniqKey="Thomassen M" first="Mads" last="Thomassen">Mads Thomassen</name></noRegion><name sortKey="Ejlertsen, Bent" sort="Ejlertsen, Bent" uniqKey="Ejlertsen B" first="Bent" last="Ejlertsen">Bent Ejlertsen</name><name sortKey="Gerdes, Anne Arie" sort="Gerdes, Anne Arie" uniqKey="Gerdes A" first="Anne-Marie" last="Gerdes">Anne-Marie Gerdes</name><name sortKey="Hansen, Thomas V O" sort="Hansen, Thomas V O" uniqKey="Hansen T" first="Thomas V. O." last="Hansen">Thomas V. O. Hansen</name><name sortKey="Jensen, Uffe Birk" sort="Jensen, Uffe Birk" uniqKey="Jensen U" first="Uffe Birk" last="Jensen">Uffe Birk Jensen</name><name sortKey="Kruse, Torben A" sort="Kruse, Torben A" uniqKey="Kruse T" first="Torben A." last="Kruse">Torben A. Kruse</name><name sortKey="Skytte, Anne Ine" sort="Skytte, Anne Ine" uniqKey="Skytte A" first="Anne-Bine" last="Skytte">Anne-Bine Skytte</name></country><country name="Italie"><region name="Toscane"><name sortKey="Caligo, Maria A" sort="Caligo, Maria A" uniqKey="Caligo M" first="Maria A." last="Caligo">Maria A. Caligo</name></region><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><name sortKey="Bernard, Loris" sort="Bernard, Loris" uniqKey="Bernard L" first="Loris" last="Bernard">Loris Bernard</name><name sortKey="Bonanni, Bernardo" sort="Bonanni, Bernardo" uniqKey="Bonanni B" first="Bernardo" last="Bonanni">Bernardo Bonanni</name><name sortKey="Dolcetti, Riccardo" sort="Dolcetti, Riccardo" uniqKey="Dolcetti R" first="Riccardo" last="Dolcetti">Riccardo Dolcetti</name><name sortKey="Manoukian, Siranoush" sort="Manoukian, Siranoush" uniqKey="Manoukian S" first="Siranoush" last="Manoukian">Siranoush Manoukian</name><name sortKey="Montagna, Marco" sort="Montagna, Marco" uniqKey="Montagna M" first="Marco" last="Montagna">Marco Montagna</name><name sortKey="Ottini, Laura" sort="Ottini, Laura" uniqKey="Ottini L" first="Laura" last="Ottini">Laura Ottini</name><name sortKey="Papi, Laura" sort="Papi, Laura" uniqKey="Papi L" first="Laura" last="Papi">Laura Papi</name><name sortKey="Peissel, Bernard" sort="Peissel, Bernard" uniqKey="Peissel B" first="Bernard" last="Peissel">Bernard Peissel</name><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><name sortKey="Tognazzo, Silvia" sort="Tognazzo, Silvia" uniqKey="Tognazzo S" first="Silvia" last="Tognazzo">Silvia Tognazzo</name><name sortKey="Zaffaroni, Daniela" sort="Zaffaroni, Daniela" uniqKey="Zaffaroni D" first="Daniela" last="Zaffaroni">Daniela Zaffaroni</name></country><country name="Suède"><region name="Svealand"><name sortKey="Liljegren, Annelie" sort="Liljegren, Annelie" uniqKey="Liljegren A" first="Annelie" last="Liljegren">Annelie Liljegren</name></region><name sortKey="Kristoffersson, Ulf" sort="Kristoffersson, Ulf" uniqKey="Kristoffersson U" first="Ulf" last="Kristoffersson">Ulf Kristoffersson</name><name sortKey="Lindblom, Annika" sort="Lindblom, Annika" uniqKey="Lindblom A" first="Annika" last="Lindblom">Annika Lindblom</name><name sortKey="Melin, Beatrice" sort="Melin, Beatrice" uniqKey="Melin B" first="Beatrice" last="Melin">Beatrice Melin</name><name sortKey="Olsson, H Kan" sort="Olsson, H Kan" uniqKey="Olsson H" first="H Kan" last="Olsson">H Kan Olsson</name><name sortKey="Stenmark Skmalm, Marie" sort="Stenmark Skmalm, Marie" uniqKey="Stenmark Skmalm M" first="Marie" last="Stenmark-Askmalm">Marie Stenmark-Askmalm</name></country><country name="Pologne"><noRegion><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name></noRegion><name sortKey="Byrski, Tomasz" sort="Byrski, Tomasz" uniqKey="Byrski T" first="Tomasz" last="Byrski">Tomasz Byrski</name><name sortKey="Cybulski, Cezary" sort="Cybulski, Cezary" uniqKey="Cybulski C" first="Cezary" last="Cybulski">Cezary Cybulski</name><name sortKey="Durda, Katarzyna" sort="Durda, Katarzyna" uniqKey="Durda K" first="Katarzyna" last="Durda">Katarzyna Durda</name><name sortKey="Gronwald, Jacek" sort="Gronwald, Jacek" uniqKey="Gronwald J" first="Jacek" last="Gronwald">Jacek Gronwald</name><name sortKey="Huzarski, Tomasz" sort="Huzarski, Tomasz" uniqKey="Huzarski T" first="Tomasz" last="Huzarski">Tomasz Huzarski</name><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><name sortKey="Jaworska, Katarzyna" sort="Jaworska, Katarzyna" uniqKey="Jaworska K" first="Katarzyna" last="Jaworska">Katarzyna Jaworska</name><name sortKey="Lubinski, 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uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name></region><name sortKey="Arnold, Norbert" sort="Arnold, Norbert" uniqKey="Arnold N" first="Norbert" last="Arnold">Norbert Arnold</name><name sortKey="Deissler, Helmut" sort="Deissler, Helmut" uniqKey="Deissler H" first="Helmut" last="Deissler">Helmut Deissler</name><name sortKey="Ditsch, Nina" sort="Ditsch, Nina" uniqKey="Ditsch N" first="Nina" last="Ditsch">Nina Ditsch</name><name sortKey="Engel, Christoph" sort="Engel, Christoph" uniqKey="Engel C" first="Christoph" last="Engel">Christoph Engel</name><name sortKey="Fiebig, Britta" sort="Fiebig, Britta" uniqKey="Fiebig B" first="Britta" last="Fiebig">Britta Fiebig</name><name sortKey="Gadzicki, Dorotehea" sort="Gadzicki, Dorotehea" uniqKey="Gadzicki D" first="Dorotehea" last="Gadzicki">Dorotehea Gadzicki</name><name sortKey="Gehrig, Andrea" sort="Gehrig, Andrea" uniqKey="Gehrig A" first="Andrea" last="Gehrig">Andrea Gehrig</name><name sortKey="Heidemann, Simone" 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Schmutzler</name><name sortKey="Sutter, Christian" sort="Sutter, Christian" uniqKey="Sutter C" first="Christian" last="Sutter">Christian Sutter</name><name sortKey="Varon Ateeva, Raymonda" sort="Varon Ateeva, Raymonda" uniqKey="Varon Ateeva R" first="Raymonda" last="Varon-Mateeva">Raymonda Varon-Mateeva</name><name sortKey="Wappenschmidt, Barbara" sort="Wappenschmidt, Barbara" uniqKey="Wappenschmidt B" first="Barbara" last="Wappenschmidt">Barbara Wappenschmidt</name></country><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Rookus, Matti" sort="Rookus, Matti" uniqKey="Rookus M" first="Matti" last="Rookus">Matti Rookus</name></region><name sortKey="Aalfs, Cora M" sort="Aalfs, Cora M" uniqKey="Aalfs C" first="Cora M." last="Aalfs">Cora M. Aalfs</name><name sortKey="Collee, J Margriet" sort="Collee, J Margriet" uniqKey="Collee J" first="J. Margriet" last="Collée">J. Margriet Collée</name><name sortKey="Hoogerbrugge, Nicoline" sort="Hoogerbrugge, Nicoline" uniqKey="Hoogerbrugge N" first="Nicoline" last="Hoogerbrugge">Nicoline Hoogerbrugge</name><name sortKey="Kriege, Mieke" sort="Kriege, Mieke" uniqKey="Kriege M" first="Mieke" last="Kriege">Mieke Kriege</name><name sortKey="Meijers Eijboer, Hanne E J" sort="Meijers Eijboer, Hanne E J" uniqKey="Meijers Eijboer H" first="Hanne E. J." last="Meijers-Heijboer">Hanne E. J. Meijers-Heijboer</name><name sortKey="Van Asperen, Christi J" sort="Van Asperen, Christi J" uniqKey="Van Asperen C" first="Christi J." last="Van Asperen">Christi J. Van Asperen</name><name sortKey="Van Der Luijt, Rob B" sort="Van Der Luijt, Rob B" uniqKey="Van Der Luijt R" first="Rob B." last="Van Der Luijt">Rob B. Van Der Luijt</name><name sortKey="Van Leeuwen, Flora E" sort="Van Leeuwen, Flora E" uniqKey="Van Leeuwen F" first="Flora E." last="Van Leeuwen">Flora E. Van Leeuwen</name><name sortKey="Van Roozendaal, K E P" sort="Van Roozendaal, K E P" uniqKey="Van Roozendaal K" first="K. E. P." last="Van Roozendaal">K. E. P. Van Roozendaal</name></country><country name="Irlande (pays)"><noRegion><name sortKey="Kennedy, M John" sort="Kennedy, M John" uniqKey="Kennedy M" first="M. John" last="Kennedy">M. John Kennedy</name></noRegion></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Singer, Christian F" sort="Singer, Christian F" uniqKey="Singer C" first="Christian F." last="Singer">Christian F. 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Gaudet</name></noRegion></country><country name="Russie"><noRegion><name sortKey="Imyanitov, Evgeny" sort="Imyanitov, Evgeny" uniqKey="Imyanitov E" first="Evgeny" last="Imyanitov">Evgeny Imyanitov</name></noRegion></country><country name="Lituanie"><noRegion><name sortKey="Janavicius, Ramunas" sort="Janavicius, Ramunas" uniqKey="Janavicius R" first="Ramunas" last="Janavicius">Ramunas Janavicius</name></noRegion></country><country name="Hongrie"><region name="Hongrie centrale"><name sortKey="Olah, Edith" sort="Olah, Edith" uniqKey="Olah E" first="Edith" last="Olah">Edith Olah</name></region><name sortKey="Vaszko, Tibor" sort="Vaszko, Tibor" uniqKey="Vaszko T" first="Tibor" last="Vaszko">Tibor Vaszko</name></country><country name="Malaisie"><noRegion><name sortKey="Teo, Soo Wang" sort="Teo, Soo Wang" uniqKey="Teo S" first="Soo-Hwang" last="Teo">Soo-Hwang Teo</name></noRegion></country><country name="Afrique du Sud"><noRegion><name sortKey="Dorfling, Cecelia M" sort="Dorfling, Cecelia M" uniqKey="Dorfling C" first="Cecelia M" last="Dorfling">Cecelia M. Dorfling</name></noRegion><name sortKey="Van Rensburg, Elizabeth J" sort="Van Rensburg, Elizabeth J" uniqKey="Van Rensburg E" first="Elizabeth J." last="Van Rensburg">Elizabeth J. Van Rensburg</name></country><country name="Hong Kong"><noRegion><name sortKey="Kwong, Ava" sort="Kwong, Ava" uniqKey="Kwong A" first="Ava" last="Kwong">Ava Kwong</name></noRegion></country><country name="Finlande"><noRegion><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name></noRegion><name sortKey="Aittom Ki, Kristiina" sort="Aittom Ki, Kristiina" uniqKey="Aittom Ki K" first="Kristiina" last="Aittom Ki">Kristiina Aittom Ki</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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